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Yes-Associated Protein (YAP) Promotes Tumorigenesis in Melanoma Cells Through Stimulation of Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1)

YAP is a critical protein in cancer development and can induce transformative phenotypes in mammary epithelial cells. Previous studies have provided evidence that YAP can contribute to the metastatic behavior of melanoma, since specific knockdown of YAP leads to reduced metastatic and invasive capac...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Xiong, Huizi, Yu, Qian, Gong, Yu, Chen, Wenjuan, Tong, Yunlei, Wang, Yao, Xu, Hui, Shi, Yuling
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686191/
https://ncbi.nlm.nih.gov/pubmed/29138479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14764-4
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