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Circulating heparan sulfate fragments attenuate histone-induced lung injury independently of histone binding
Extracellular histones are cationic damage-associated molecular pattern molecules capable of directly inducing cellular injury via charge-mediated interactions with plasma membranes. Accordingly, histones released into the plasma during critical illness are known to contribute to the onset and propa...
Shranjeno v:
| izdano v: | Shock |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5685884/ https://ncbi.nlm.nih.gov/pubmed/28538085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000907 |
| Oznake: |
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