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Heparan Sulfate-Independent Cell Binding and Infection with Furin-Precleaved Papillomavirus Capsids

Papillomavirus infection normally involves virion binding to cell surface heparan sulfate proteoglycans (HSPGs). However, we found that human papillomavirus type 16 pseudovirions efficiently bound and infected cells lacking HSPGs if their L2 capsid protein was precleaved by furin, a cellular proteas...

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Detalles Bibliográficos
Autores principales: Day, Patricia M., Lowy, Douglas R., Schiller, John T.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593329/
https://ncbi.nlm.nih.gov/pubmed/18829767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01631-08
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