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Heparan Sulfate-Independent Cell Binding and Infection with Furin-Precleaved Papillomavirus Capsids

Papillomavirus infection normally involves virion binding to cell surface heparan sulfate proteoglycans (HSPGs). However, we found that human papillomavirus type 16 pseudovirions efficiently bound and infected cells lacking HSPGs if their L2 capsid protein was precleaved by furin, a cellular proteas...

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Detalhes bibliográficos
Main Authors: Day, Patricia M., Lowy, Douglas R., Schiller, John T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593329/
https://ncbi.nlm.nih.gov/pubmed/18829767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01631-08
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