Substrate Specificity of the Kinase P-TEFb towards the RNA Polymerase II C-Terminal Domain

The positive transcription elongation factor b (P-TEFb) promotes transcription elongation through phosphorylation of the RNA polymerase II C-terminal domain. This process is not well understood, partly due to difficulties in determining the specificity of P-TEFb toward the various heptad repeat moti...

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Detalles Bibliográficos
Publicado en:Biophys J
Main Authors: Gibbs, Eric B., Laremore, Tatiana N., Usher, Grace A., Portz, Bede, Cook, Erik C., Showalter, Scott A.
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2017
Assuntos:
Biophysical Letters
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685781/
https://ncbi.nlm.nih.gov/pubmed/28992937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.09.011
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