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The C-terminal domain of RNA polymerase II is a multivalent targeting sequence that supports Drosophila development with only consensus heptads

The carboxy-terminal domain (CTD) of RNA polymerase II (Pol II) is composed of repeats of the consensus YSPTSPS, and is an essential binding scaffold for transcription-associated factors. Metazoan CTDs have well-conserved lengths and sequence compositions arising from the evolution of divergent moti...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Lu, Feiyue, Portz, Bede, Gilmour, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6440539/
https://ncbi.nlm.nih.gov/pubmed/30765194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.01.008
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