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FRET Analysis of the Promiscuous yet Specific Interactions of the HIV-1 Vpu Transmembrane Domain

The Vpu protein of HIV-1 functions to downregulate cell surface localization of host proteins involved in the innate immune response to viral infection. For several target proteins, including the NTB-A and PVR receptors and the host restriction factor tetherin, this antagonism is carried out via dir...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Cole, Gregory B., Reichheld, Sean E., Sharpe, Simon
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685779/
https://ncbi.nlm.nih.gov/pubmed/29117523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.09.010
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