Identification of Amino Acids in the Human Tetherin Transmembrane Domain Responsible for HIV-1 Vpu Interaction and Susceptibility

Tetherin, also known as BST-2/CD317/HM1.24, is an antiviral cellular protein that inhibits the release of HIV-1 particles from infected cells. HIV-1 viral protein U (Vpu) is a specific antagonist of human tetherin that might contribute to the high virulence of HIV-1. In this study, we show that thre...

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Main Authors: Kobayashi, Tomoko, Ode, Hirotaka, Yoshida, Takeshi, Sato, Kei, Gee, Peter, Yamamoto, Seiji P., Ebina, Hirotaka, Strebel, Klaus, Sato, Hironori, Koyanagi, Yoshio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020002/
https://ncbi.nlm.nih.gov/pubmed/21068238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01668-10
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