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Morphological adaptations in breast cancer cells as a function of prolonged passaging on compliant substrates

Standard tissue culture practices involve propagating cells on tissue culture polystyrene (TCP) dishes, which are flat, 2-dimensional (2D) and orders of magnitude stiffer than most tissues in the body. Such simplified conditions lead to phenotypical cell changes and altered cell behaviors. Hence, mu...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Syed, Sana, Schober, Joseph, Blanco, Alexandra, Zustiak, Silviya Petrova
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685588/
https://ncbi.nlm.nih.gov/pubmed/29136040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187853
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