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Morphological adaptations in breast cancer cells as a function of prolonged passaging on compliant substrates

Standard tissue culture practices involve propagating cells on tissue culture polystyrene (TCP) dishes, which are flat, 2-dimensional (2D) and orders of magnitude stiffer than most tissues in the body. Such simplified conditions lead to phenotypical cell changes and altered cell behaviors. Hence, mu...

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Publicat a:PLoS One
Autors principals: Syed, Sana, Schober, Joseph, Blanco, Alexandra, Zustiak, Silviya Petrova
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685588/
https://ncbi.nlm.nih.gov/pubmed/29136040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187853
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