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Simple Polyacrylamide-based Multiwell Stiffness Assay for the Study of Stiffness-dependent Cell Responses

Currently, most of the in vitro cell research is performed on rigid tissue culture polystyrene (~1 GPa), while most cells in the body are attached to a matrix that is elastic and much softer (0.1 – 100 kPa). Since such stiffness mismatch greatly affects cell responses, there is a strong interest in...

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Pubblicato in:J Vis Exp
Autori principali: Syed, Sana, Karadaghy, Amin, Zustiak, Silviya
Natura: Artigo
Lingua:Inglês
Pubblicazione: MyJove Corporation 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4401385/
https://ncbi.nlm.nih.gov/pubmed/25866916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52643
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