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Micro-Clotting of Platelet-Rich Plasma Upon Loading in Hydrogel Microspheres Leads to Prolonged Protein Release and Slower Microsphere Degradation

Platelet-rich plasma (PRP) is an autologous blood product that contains a variety of growth factors (GFs) that are released upon platelet activation. Despite some therapeutic potential of PRP in vitro, in vivo data are not convincing. Bolus injection of PRP is cleared rapidly from the body diminishi...

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Detalhes bibliográficos
Publicado no:Polymers (Basel)
Main Authors: Choi, Miran Hannah, Blanco, Alexandra, Stealey, Samuel, Duan, Xin, Case, Natasha, Sell, Scott Allen, Rai, Muhammad Farooq, Zustiak, Silviya Petrova
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7464943/
https://ncbi.nlm.nih.gov/pubmed/32751604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/polym12081712
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