The prohibitin-binding compound fluorizoline induces apoptosis in chronic lymphocytic leukemia cells through the upregulation of NOXA and synergizes with ibrutinib, 5-aminoimidazole-4-carboxamide riboside or venetoclax

Eitemau Tebyg

• A novel prohibitin-binding compound induces the mitochondrial apoptotic pathway through NOXA and BIM upregulation
  gan: Moncunill-Massaguer, Cristina, et al.
  Cyhoeddwyd: (2015)
• Targeting prohibitins induces apoptosis in acute myeloid leukemia cells
  gan: Pomares, Helena, et al.
  Cyhoeddwyd: (2016)
• Activation of the Integrated Stress Response and ER Stress Protect from Fluorizoline-Induced Apoptosis in HEK293T and U2OS Cell Lines
  gan: Saura-Esteller, José, et al.
  Cyhoeddwyd: (2021)
• Inhibition of 5-aminoimidazole-4-carboxamide ribotide transformylase, adenosine deaminase and 5'-adenylate deaminase by polyglutamates of methotrexate and oxidized folates and by 5-aminoimidazole-4-carboxamide riboside and ribotide.
  gan: Baggott, J E, et al.
  Cyhoeddwyd: (1986)
• The prohibitin-binding compound fluorizoline affects multiple components of the translational machinery and inhibits protein synthesis
  gan: Zabolocki, Michael, et al.
  Cyhoeddwyd: (2020)