Targeting prohibitins induces apoptosis in acute myeloid leukemia cells

Fluorizoline is a new synthetic molecule that induces apoptosis by selectively targeting prohibitins (PHBs). In this study, the pro-apoptotic effect of fluorizoline was assessed in two cell lines and 21 primary samples from patients with debut of acute myeloid leukemia (AML). Fluorizoline induced ap...

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Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Pomares, Helena, Palmeri, Claudia M, Iglesias-Serret, Daniel, Moncunill-Massaguer, Cristina, Saura-Esteller, José, Núñez-Vázquez, Sonia, Gamundi, Enric, Arnan, Montserrat, Preciado, Sara, Albericio, Fernando, Lavilla, Rodolfo, Pons, Gabriel, González-Barca, Eva M, Cosialls, Ana M, Gil, Joan
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323132/
https://ncbi.nlm.nih.gov/pubmed/27542247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11333
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