Cargando...
Botulinum toxins A and E inflict dynamic destabilization on t-SNARE to impair SNARE assembly and membrane fusion
Botulinum toxins (BoNT) A and E block neurotransmitter release by specifically cleaving the C- terminal ends of SNAP-25, a plasma membrane SNARE protein. Here, we find that SNAP-25A and E, the cleavage products of BoNT A and E respectively, terminate membrane fusion via completely different mechanis...
Gardado en:
| Publicado en: | Structure |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5685167/ https://ncbi.nlm.nih.gov/pubmed/29033286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2017.09.004 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|