Intestinal Alkaline Phosphatase Attenuates Alcohol-Induced Hepatosteatosis in Mice

BACKGROUNDS & AIMS: Bacterially-derived factors from the gut play a major role in the activation of inflammatory pathways in the liver and in the pathogenesis of alcoholic liver disease. The intestinal brush-border enzyme intestinal alkaline phosphatase (IAP) detoxifies a variety of bacterial pr...

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Udgivet i:Dig Dis Sci
Main Authors: Hamarneh, Sulaiman R., Kim, Byeong-Moo, Kaliannan, Kanakaraju, Morrison, Sara A., Tantillo, Tyler J., Tao, Qingsong, Rafat Mohamed, Mussa M., Ramirez, Juan M., Karas, Aaron, Liu, Wei, Hu, Dong, Teshager, Abeba, Gul, Sarah Shireen, Economopoulos, Konstantinos P., Bhan, Atul K., Malo, Madhu S., Choi, Michael Y., Hodin, Richard A.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5684583/
https://ncbi.nlm.nih.gov/pubmed/28424943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10620-017-4576-0
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