Inhibition of Murine Cytomegalovirus Infection in Animals by RNase P-Associated External Guide Sequences

External guide sequence (EGS) RNAs are associated with ribonuclease P (RNase P), a tRNA processing enzyme, and represent promising agents for gene-targeting applications as they can direct RNase-P-mediated cleavage of a target mRNA. Using murine cytomegalovirus (MCMV) as a model system, we examined...

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Publicado en:Mol Ther Nucleic Acids
Main Authors: Li, Wei, Sheng, Jingxue, Xu, Mengqiong, Vu, Gia-Phong, Yang, Zhu, Liu, Yujun, Sun, Xu, Trang, Phong, Lu, Sangwei, Liu, Fenyong
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Gene & Cell Therapy 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5684469/
https://ncbi.nlm.nih.gov/pubmed/29246310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2017.10.007
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