Longrange PCR-based next-generation sequencing in pharmacokinetics and pharmacodynamics study of propofol among patients under general anaesthesia

The individual response of patients to propofol results from the influence of genetic factors. However, the state of knowledge in this matter still remains insufficient. The aim of our study was to determine genetic predictors of variable pharmacokinetics and pharmacodynamics of propofol within sele...

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Published in:Sci Rep
Main Authors: Zakerska-Banaszak, Oliwia, Skrzypczak-Zielinska, Marzena, Tamowicz, Barbara, Mikstacki, Adam, Walczak, Michal, Prendecki, Michal, Dorszewska, Jolanta, Pollak, Agnieszka, Lechowicz, Urszula, Oldak, Monika, Huminska-Lisowska, Kinga, Molinska-Glura, Marta, Szalata, Marlena, Slomski, Ryszard
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5684313/
https://ncbi.nlm.nih.gov/pubmed/29133890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15657-2
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