Impact of CYP2E1, GSTA1 and GSTP1 gene variants on serum alpha glutathione S-transferase level in patients undergoing anaesthesia

BACKGROUND: The serum glutathione S-transferase alpha (α-GST) concentration has been used as a marker of hepatic condition. After sevoflurane anaesthesia a mild impairment of hepatocellular integrity was observed. Genetic polymorphisms in CYP2E1, GSTA1 and GSTP1 genes, affecting enzymes activity, ma...

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Detalhes bibliográficos
Publicado no:BMC Med Genet
Main Authors: Mikstacki, Adam, Skrzypczak-Zielinska, Marzena, Zakerska-Banaszak, Oliwia, Tamowicz, Barbara, Skibinska, Maria, Molinska-Glura, Marta, Szalata, Marlena, Slomski, Ryszard
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868025/
https://ncbi.nlm.nih.gov/pubmed/27179909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-016-0302-6
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