The effect of UGT1A9, CYP2B6 and CYP2C9 genes polymorphism on individual differences in propofol pharmacokinetics among Polish patients undergoing general anaesthesia

Propofol (2,6-diisopropylphenol) is one of the safest and most commonly used anaesthetic agents for intravenous general anaesthesia. However, in clinical practice, a large inter-individual variability in response to propofol is observed. To limit the risk of adverse effects, pharmacogenetic investig...

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Detalhes bibliográficos
Publicado no:J Appl Genet
Main Authors: Mikstacki, Adam, Zakerska-Banaszak, Oliwia, Skrzypczak-Zielinska, Marzena, Tamowicz, Barbara, Prendecki, Michał, Dorszewska, Jolanta, Molinska-Glura, Marta, Waszak, Malgorzata, Slomski, Ryszard
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2016
Assuntos:
Human Genetics • Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391385/
https://ncbi.nlm.nih.gov/pubmed/27826892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13353-016-0373-2
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