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High-Resolution Melting Analysis of the TPMT Gene: A Study in the Polish Population

The thiopurine S-methyltransferase (TPMT) gene encoding thiopurine methyltransferase is a crucial enzyme in metabolism of thiopurine drugs: azathioprine and 6-mercoptopurine, which are used in the treatment of leukemia or inflammatory bowel diseases. Genetic polymorphism of the TPMT gene correlates...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Skrzypczak-Zielinska, Marzena, Borun, Pawel, Milanowska, Katarzyna, Jakubowska-Burek, Ludwika, Zakerska, Oliwia, Dobrowolska-Zachwieja, Agnieszka, Plawski, Andrzej, Froster, Ursula G., Szalata, Marlena, Slomski, Ryszard
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552168/
https://ncbi.nlm.nih.gov/pubmed/23252704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/gtmb.2012.0192
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