Is Polymorphism in the Apoptosis and Inflammatory Pathway Genes Associated With a Primary Response to Anti-TNF Therapy in Crohn’s Disease Patients?

Anti-tumor necrosis factor (TNF) therapy is used for the induction and maintenance of remission in Crohn’s disease (CD) patients. However, primary nonresponders to initial treatment constitute 20%–40% of cases. The causes of this phenomenon are still unknown. In this study, we aimed to determine the...

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Publicat a:Front Pharmacol
Autors principals: Walczak, Michal, Lykowska-Szuber, Liliana, Plucinska, Marianna, Stawczyk-Eder, Kamila, Zakerska-Banaszak, Oliwia, Eder, Piotr, Krela-Kazmierczak, Iwona, Michalak, Michal, Zywicki, Marek, Karlowski, Wojciech M., Szalata, Marlena, Dobrowolska, Agnieszka, Slomski, Ryszard, Skrzypczak-Zielinska, Marzena
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7456829/
https://ncbi.nlm.nih.gov/pubmed/32922288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.01207
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