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Shedding of Microvesicles from Microglia Contributes to the Effects Induced by Metabotropic Glutamate Receptor 5 Activation on Neuronal Death

Metabotropic glutamate (mGlu) receptor 5 is involved in neuroinflammation and has been shown to mediate reduced inflammation and neurotoxicity and to modify microglia polarization. On the other hand, blockade of mGlu5 receptor results in inhibition of microglia activation. To dissect this controvers...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Beneventano, Martina, Spampinato, Simona F., Merlo, Sara, Chisari, Mariangela, Platania, Paola, Ragusa, Marco, Purrello, Michele, Nicoletti, Ferdinando, Sortino, Maria Angela
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5684115/
https://ncbi.nlm.nih.gov/pubmed/29170640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00812
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