Glial metabotropic glutamate receptor-4 increases maturation and survival of oligodendrocytes

Group III metabotropic glutamate (mGlu) receptors mediate important neuroprotective and anti-inflammatory effects. Stimulation of mGlu4 receptor reduces neuroinflammation in a mouse model of experimental autoimmune encephalomyelitis (EAE) whereas mGlu4 knockout mice display exacerbated EAE clinical...

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Detalles Bibliográficos
Publicado en:Front Cell Neurosci
Main Authors: Spampinato, Simona Federica, Merlo, Sara, Chisari, Mariangela, Nicoletti, Ferdinando, Sortino, Maria Angela
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2015
Assuntos:
Neuroscience
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294134/
https://ncbi.nlm.nih.gov/pubmed/25642169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00462
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