Surfactant protein A down-regulates epidermal growth factor receptor by mechanisms different from those of surfactant protein D

We recently reported that the lectin surfactant protein D (SP-D) suppresses epidermal growth factor receptor (EGFR) signaling by interfering with ligand binding to EGFR through an interaction between the carbohydrate-recognition domain (CRD) of SP-D and N-glycans of EGFR. Here, we report that surfac...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Hasegawa, Yoshihiro, Takahashi, Motoko, Ariki, Shigeru, Saito, Atsushi, Uehara, Yasuaki, Takamiya, Rina, Kuronuma, Koji, Chiba, Hirofumi, Sakuma, Yuji, Takahashi, Hiroki, Kuroki, Yoshio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5682966/
https://ncbi.nlm.nih.gov/pubmed/28972165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.800771
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