Surfactant Protein D Inhibits Adherence of Uropathogenic Escherichia coli to the Bladder Epithelial Cells and the Bacterium-induced Cytotoxicity: A POSSIBLE FUNCTION IN URINARY TRACT

The adherence of uropathogenic Escherichia coli (UPEC) to the host urothelial surface is the first step for establishing UPEC infection. Uroplakin Ia (UPIa), a glycoprotein expressed on bladder urothelium, serves as a receptor for FimH, a lectin located at bacterial pili, and their interaction initi...

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Autori principali: Kurimura, Yuichiro, Nishitani, Chiaki, Ariki, Shigeru, Saito, Atsushi, Hasegawa, Yoshihiro, Takahashi, Motoko, Hashimoto, Jiro, Takahashi, Satoshi, Tsukamoto, Taiji, Kuroki, Yoshio
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501034/
https://ncbi.nlm.nih.gov/pubmed/23012359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.380287
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