Disruption of the structural and functional features of surfactant protein A by acrolein in cigarette smoke

The extent to which defective innate immune responses contribute to chronic obstructive pulmonary disease (COPD) is not fully understood. Pulmonary surfactant protein A (SP-A) plays an important role in regulating innate immunity in the lungs. In this study, we hypothesised that cigarette smoke (CS)...

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I publikationen:Sci Rep
Huvudupphovsmän: Takamiya, Rina, Uchida, Koji, Shibata, Takahiro, Maeno, Toshitaka, Kato, Masaki, Yamaguchi, Yoshiki, Ariki, Shigeru, Hasegawa, Yoshihiro, Saito, Atsushi, Miwa, Soichi, Takahashi, Hiroki, Akaike, Takaaki, Kuroki, Yoshio, Takahashi, Motoko
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2017
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559459/
https://ncbi.nlm.nih.gov/pubmed/28814727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08588-5
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