Suppression of Heregulin β Signaling by the Single N-Glycan Deletion Mutant of Soluble ErbB3 Protein

Heregulin signaling is involved in various tumor proliferations and invasions; thus, receptors of heregulin are targets for the cancer therapy. In this study we examined the suppressing effects of extracellular domains of ErbB2, ErbB3, and ErbB4 (soluble ErbB (sErbB)) on heregulin β signaling in hum...

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Detalhes bibliográficos
Main Authors: Takahashi, Motoko, Hasegawa, Yoshihiro, Ikeda, Yoshitaka, Wada, Yoshinao, Tajiri, Michiko, Ariki, Shigeru, Takamiya, Rina, Nishitani, Chiaki, Araki, Motoko, Yamaguchi, Yoshiki, Taniguchi, Naoyuki, Kuroki, Yoshio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829142/
https://ncbi.nlm.nih.gov/pubmed/24097984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.491902
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