Antitumor immunity is defective in T cell–specific microRNA-155–deficient mice and is rescued by immune checkpoint blockade

MicroRNA-155 (miR-155) regulates antitumor immune responses. However, its specific functions within distinct immune cell types have not been delineated in conditional KO mouse models. In this study, we investigated the role of miR-155 specifically within T cells during the immune response to syngene...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Huffaker, Thomas B., Lee, Soh-Hyun, Tang, William W., Wallace, Jared A., Alexander, Margaret, Runtsch, Marah C., Larsen, Dane K., Thompson, Jacob, Ramstead, Andrew G., Voth, Warren P., Hu, Ruozhen, Round, June L., Williams, Matthew A., O'Connell, Ryan M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2017
Gaiak:
Immunology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5682963/
https://ncbi.nlm.nih.gov/pubmed/28912267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.808121
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