miR-155 promotes FLT3-ITD–induced myeloproliferative disease through inhibition of the interferon response

FLT3-ITD(+) acute myeloid leukemia (AML) accounts for ∼25% of all AML cases and is a subtype that carries a poor prognosis. microRNA-155 (miR-155) is specifically overexpressed in FLT3-ITD(+) AML compared with FLT3 wild-type (FLT3-WT) AML and is critical for the growth of FLT3-ITD(+) AML cells in vi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Blood
Egile Nagusiak: Wallace, Jared A., Kagele, Dominique A., Eiring, Anna M., Kim, Carissa N., Hu, Ruozhen, Runtsch, Marah C., Alexander, Margaret, Huffaker, Thomas B., Lee, Soh-Hyun, Patel, Ami B., Mosbruger, Timothy L., Voth, Warren P., Rao, Dinesh S., Miles, Rodney R., Round, June L., Deininger, Michael W., O’Connell, Ryan M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2017
Gaiak:
Myeloid Neoplasia
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465836/
https://ncbi.nlm.nih.gov/pubmed/28432220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-09-740209
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak