SIRT3 protects hepatocytes from oxidative injury by enhancing ROS scavenging and mitochondrial integrity

Evidences of oxidative stress and mitochondrial dysfunction have been recognized in most of clinical and experimental liver diseases. SIRT3, a member of NAD(+)-dependent deacetylases, is mainly localized in mitochondria. So far, the role of SIRT3 in protecting hepatocytes against oxidative stress re...

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Bibliographic Details
Published in:Cell Death Dis
Main Authors: Liu, Jingxin, Li, Dan, Zhang, Tian, Tong, Qiang, Ye, Richard Dequan, Lin, Ligen
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680927/
https://ncbi.nlm.nih.gov/pubmed/29072685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.564
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