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An Integrated Mitochondrial ROS Production and Scavenging Model: Implications for Heart Failure
It has been observed experimentally that cells from failing hearts exhibit elevated levels of reactive oxygen species (ROS) upon increases in energetic workload. One proposed mechanism for this behavior is mitochondrial Ca(2+) mismanagement that leads to depletion of ROS scavengers. Here, we present...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3882515/ https://ncbi.nlm.nih.gov/pubmed/24359755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.11.007 |
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