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Hydrogen peroxide diffusion and scavenging shapes mitochondrial network instability and failure by sensitizing ROS-induced ROS release

The mitochondrial network of cardiac cells is finely tuned for ATP delivery to sites of energy demand; however, emergent phenomena, such as mitochondrial transmembrane potential oscillations or propagating waves of depolarization have been observed under metabolic stress. While regenerative signalin...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Millare, Brent, O’Rourke, Brian, Trayanova, Natalia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7519669/
https://ncbi.nlm.nih.gov/pubmed/32978406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-71308-z
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