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SIRT3 protects hepatocytes from oxidative injury by enhancing ROS scavenging and mitochondrial integrity
Evidences of oxidative stress and mitochondrial dysfunction have been recognized in most of clinical and experimental liver diseases. SIRT3, a member of NAD(+)-dependent deacetylases, is mainly localized in mitochondria. So far, the role of SIRT3 in protecting hepatocytes against oxidative stress re...
Enregistré dans:
| Publié dans: | Cell Death Dis |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5680927/ https://ncbi.nlm.nih.gov/pubmed/29072685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.564 |
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