Small molecules for fat combustion: targeting obesity

بواسطة Liu, Jingxin, Wang, Yitao, Lin, Ligen
الحاوية / القاعدة Acta Pharm Sin B (2019)

SIRT3 Acts as a Positive Autophagy Regulator to Promote Lipid Mobilization in Adipocytes via Activating AMPK

بواسطة Zhang, Tian, Liu, Jingxin, Tong, Qiang, Lin, Ligen
الحاوية / القاعدة Int J Mol Sci (2020)

The drug likeness analysis of anti-inflammatory clerodane diterpenoids

بواسطة Feng, Zheling, Cao, Jun, Zhang, Qingwen, Lin, Ligen
الحاوية / القاعدة Chin Med (2020)

Myricanol modulates skeletal muscle–adipose tissue crosstalk to alleviate high‐fat diet‐induced obesity and insulin resistance

بواسطة Shen, Shengnan, Liao, Qiwen, Zhang, Tian, Pan, Ruile, Lin, Ligen
الحاوية / القاعدة Br J Pharmacol (2019)

Xanthones, A Promising Anti-Inflammatory Scaffold: Structure, Activity, and Drug Likeness Analysis

بواسطة Feng, Zheling, Lu, Xiuqiang, Gan, Lishe, Zhang, Qingwen, Lin, Ligen
الحاوية / القاعدة Molecules (2020)

Schisandrin B reverses doxorubicin resistance through inhibiting P-glycoprotein and promoting proteasome-mediated degradation of survivin

بواسطة Wang, Shengpeng, Wang, Anqi, Shao, Min, Lin, Ligen, Li, Peng, Wang, Yitao
الحاوية / القاعدة Sci Rep (2017)

Induction of ferroptosis and mitochondrial dysfunction by oxidative stress in PC12 cells

بواسطة Wu, Chuanhong, Zhao, Wenwen, Yu, Jie, Li, Shaojing, Lin, Ligen, Chen, Xiuping
الحاوية / القاعدة Sci Rep (2018)

Antioxidant and Hepatoprotective Effect of Penthorum chinense Pursh Extract against t-BHP-Induced Liver Damage in L02 Cells

بواسطة Hu, Yangyang, Wang, Shengpeng, Wang, Anqi, Lin, Ligen, Chen, Meiwan, Wang, Yitao
الحاوية / القاعدة Molecules (2015)

SIRT3 promotes lipophagy and chaperon-mediated autophagy to protect hepatocytes against lipotoxicity

بواسطة Zhang, Tian, Liu, Jingxin, Shen, Shengnan, Tong, Qiang, Ma, Xiaojun, Lin, Ligen
الحاوية / القاعدة Cell Death Differ (2019)

SIRT3 protects hepatocytes from oxidative injury by enhancing ROS scavenging and mitochondrial integrity

بواسطة Liu, Jingxin, Li, Dan, Zhang, Tian, Tong, Qiang, Ye, Richard Dequan, Lin, Ligen
الحاوية / القاعدة Cell Death Dis (2017)

A Mechanistic Overview of Triptolide and Celastrol, Natural Products from Tripterygium wilfordii Hook F

بواسطة Chen, Shao-Ru, Dai, Yan, Zhao, Jing, Lin, Ligen, Wang, Yitao, Wang, Ying
الحاوية / القاعدة Front Pharmacol (2018)

Two New N-Oxide Alkaloids from Stemona cochinchinensis

بواسطة Lin, Ligen, Bao, Han, Wang, Anqi, Tang, Chunping, Dien, Pham-Huu, Ye, Yang
الحاوية / القاعدة Molecules (2014)

Small molecule‐driven SIRT3‐autophagy‐mediated NLRP3 inflammasome inhibition ameliorates inflammatory crosstalk between macrophages and adipocytes

بواسطة Zhang, Tian, Fang, Zhujun, Linghu, Ke‐Gang, Liu, Jingxin, Gan, Lishe, Lin, Ligen
الحاوية / القاعدة Br J Pharmacol (2020)

Adipocyte expression of PU.1 transcription factor causes insulin resistance through upregulation of inflammatory cytokine gene expression and ROS production

بواسطة Lin, Ligen, Pang, Weijun, Chen, Keyun, Wang, Fei, Gengler, Jon, Sun, Yuxiang, Tong, Qiang
منشور في 2012

1,3,6,7‐Tetrahydroxy‐8‐prenylxanthone ameliorates inflammatory responses resulting from the paracrine interaction of adipocytes and macrophages

بواسطة Li, Dan, Liu, Qianyu, Sun, Wen, Chen, Xiuping, Wang, Ying, Sun, Yuxiang, Lin, Ligen
الحاوية / القاعدة Br J Pharmacol (2018)

Myricanol rescues dexamethasone‐induced muscle dysfunction via a sirtuin 1‐dependent mechanism

بواسطة Shen, Shengnan, Liao, Qiwen, Liu, Jingxin, Pan, Ruile, Lee, Simon Ming‐Yuen, Lin, Ligen
الحاوية / القاعدة J Cachexia Sarcopenia Muscle (2019)

Ablations of Ghrelin and Ghrelin Receptor Exhibit Differential Metabolic Phenotypes and Thermogenic Capacity during Aging

بواسطة Ma, Xiaojun, Lin, Ligen, Qin, Guijun, Lu, Xinping, Fiorotto, Marta, Dixit, Vishwa D., Sun, Yuxiang
منشور في 2011

Ghrelin Receptor Regulates Appetite and Satiety during Aging in Mice by Regulating Meal Frequency and Portion Size but Not Total Food Intake(1)(2)(3)(4)

بواسطة Lin, Ligen, Nuotio-Antar, Alli M., Ma, Xiaojun, Liu, Feng, Fiorotto, Marta L., Sun, Yuxiang
منشور في 2014

Quantitative Proteomics Reveals Cellular Off-Targets of a DDR1 Inhibitor

بواسطة Xu, Jiaqian, Zhang, Zhang, Lin, Ligen, Sun, Hongyan, White, Lorenzo V., Ding, Ke, Li, Zhengqiu
الحاوية / القاعدة ACS Med Chem Lett (2020)

GHS-R in brown fat potentiates differential thermogenic responses under metabolic and thermal stresses

بواسطة Lee, Jong Han, Lin, Ligen, Ye, Xiangcang, Wolfrum, Christian, Chen, Yingjie, Guo, Shaodong, Sun, Yuxiang
الحاوية / القاعدة PLoS One (2021)