Myricanol rescues dexamethasone‐induced muscle dysfunction via a sirtuin 1‐dependent mechanism

BACKGROUND: Muscle atrophy and weakness are adverse effects of high dose or the sustained usage of glucocorticoids. Loss of mitochondria and degradation of protein are highly correlated with muscle dysfunction. The deacetylase sirtuin 1 (SIRT1) plays a vital role in muscle remodelling. The current s...

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Bibliografiske detaljer
Udgivet i:J Cachexia Sarcopenia Muscle
Main Authors: Shen, Shengnan, Liao, Qiwen, Liu, Jingxin, Pan, Ruile, Lee, Simon Ming‐Yuen, Lin, Ligen
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463464/
https://ncbi.nlm.nih.gov/pubmed/30793539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12393
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