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The interplay between HLA‐B27 and ERAP1/ERAP2 aminopeptidases: from anti‐viral protection to spondyloarthritis

The human leukocyte antigen class I gene HLA‐B27 is the strongest risk factor for ankylosing spondylitis (AS), a chronic inflammatory arthritic disorder. More recently, the Endoplasmic Reticulum Aminopeptidase (ERAP) 1 and 2 genes have been identified by genome wide association studies (GWAS) as add...

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Bibliografiske detaljer
Udgivet i:Clin Exp Immunol
Main Authors: Vitulano, C., Tedeschi, V., Paladini, F., Sorrentino, R., Fiorillo, M. T.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680067/
https://ncbi.nlm.nih.gov/pubmed/28759104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.13020
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