Neuropathological and transcriptomic characteristics of the aged brain

As more people live longer, age-related neurodegenerative diseases are an increasingly important societal health issue. Treatments targeting specific pathologies such as amyloid beta in Alzheimer’s disease (AD) have not led to effective treatments, and there is increasing evidence of a disconnect be...

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Vydáno v:eLife
Hlavní autoři: Miller, Jeremy A, Guillozet-Bongaarts, Angela, Gibbons, Laura E, Postupna, Nadia, Renz, Anne, Beller, Allison E, Sunkin, Susan M, Ng, Lydia, Rose, Shannon E, Smith, Kimberly A, Szafer, Aaron, Barber, Chris, Bertagnolli, Darren, Bickley, Kristopher, Brouner, Krissy, Caldejon, Shiella, Chapin, Mike, Chua, Mindy L, Coleman, Natalie M, Cudaback, Eiron, Cuhaciyan, Christine, Dalley, Rachel A, Dee, Nick, Desta, Tsega, Dolbeare, Tim A, Dotson, Nadezhda I, Fisher, Michael, Gaudreault, Nathalie, Gee, Garrett, Gilbert, Terri L, Goldy, Jeff, Griffin, Fiona, Habel, Caroline, Haradon, Zeb, Hejazinia, Nika, Hellstern, Leanne L, Horvath, Steve, Howard, Kim, Howard, Robert, Johal, Justin, Jorstad, Nikolas L, Josephsen, Samuel R, Kuan, Chihchau L, Lai, Florence, Lee, Eric, Lee, Felix, Lemon, Tracy, Li, Xianwu, Marshall, Desiree A, Melchor, Jose, Mukherjee, Shubhabrata, Nyhus, Julie, Pendergraft, Julie, Potekhina, Lydia, Rha, Elizabeth Y, Rice, Samantha, Rosen, David, Sapru, Abharika, Schantz, Aimee, Shen, Elaine, Sherfield, Emily, Shi, Shu, Sodt, Andy J, Thatra, Nivretta, Tieu, Michael, Wilson, Angela M, Montine, Thomas J, Larson, Eric B, Bernard, Amy, Crane, Paul K, Ellenbogen, Richard G, Keene, C Dirk, Lein, Ed
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2017
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679757/
https://ncbi.nlm.nih.gov/pubmed/29120328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.31126
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