Neuropathological and transcriptomic characteristics of the aged brain

As more people live longer, age-related neurodegenerative diseases are an increasingly important societal health issue. Treatments targeting specific pathologies such as amyloid beta in Alzheimer’s disease (AD) have not led to effective treatments, and there is increasing evidence of a disconnect be...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Miller, Jeremy A, Guillozet-Bongaarts, Angela, Gibbons, Laura E, Postupna, Nadia, Renz, Anne, Beller, Allison E, Sunkin, Susan M, Ng, Lydia, Rose, Shannon E, Smith, Kimberly A, Szafer, Aaron, Barber, Chris, Bertagnolli, Darren, Bickley, Kristopher, Brouner, Krissy, Caldejon, Shiella, Chapin, Mike, Chua, Mindy L, Coleman, Natalie M, Cudaback, Eiron, Cuhaciyan, Christine, Dalley, Rachel A, Dee, Nick, Desta, Tsega, Dolbeare, Tim A, Dotson, Nadezhda I, Fisher, Michael, Gaudreault, Nathalie, Gee, Garrett, Gilbert, Terri L, Goldy, Jeff, Griffin, Fiona, Habel, Caroline, Haradon, Zeb, Hejazinia, Nika, Hellstern, Leanne L, Horvath, Steve, Howard, Kim, Howard, Robert, Johal, Justin, Jorstad, Nikolas L, Josephsen, Samuel R, Kuan, Chihchau L, Lai, Florence, Lee, Eric, Lee, Felix, Lemon, Tracy, Li, Xianwu, Marshall, Desiree A, Melchor, Jose, Mukherjee, Shubhabrata, Nyhus, Julie, Pendergraft, Julie, Potekhina, Lydia, Rha, Elizabeth Y, Rice, Samantha, Rosen, David, Sapru, Abharika, Schantz, Aimee, Shen, Elaine, Sherfield, Emily, Shi, Shu, Sodt, Andy J, Thatra, Nivretta, Tieu, Michael, Wilson, Angela M, Montine, Thomas J, Larson, Eric B, Bernard, Amy, Crane, Paul K, Ellenbogen, Richard G, Keene, C Dirk, Lein, Ed
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679757/
https://ncbi.nlm.nih.gov/pubmed/29120328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.31126
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