Wild Type Bone Marrow Transplant Partially Reverses Neuroinflammation in Progranulin-Deficient Mice

Frontotemporal dementia (FTD) is a neurodegenerative disease with devastating changes in behavioral performance and social function. Mutations in the progranulin gene (GRN) are one of the most common causes of inherited FTD due to reduced progranulin expression or activity, including in brain where...

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Bibliografiske detaljer
Udgivet i:Lab Invest
Main Authors: Yang, Yue, Aloi, Macarena S., Cudaback, Eiron, Josephsen, Samuel R., Rice, Samantha J., Jorstad, Nikolas L., Keene, C. Dirk, Montine, Thomas J.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218738/
https://ncbi.nlm.nih.gov/pubmed/25199051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2014.113
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