The Expression Level of CB(1) and CB(2) Receptors Determines Their Efficacy at Inducing Apoptosis in Astrocytomas

BACKGROUND: Cannabinoids represent unique compounds for treating tumors, including astrocytomas. Whether CB(1) and CB(2) receptors mediate this therapeutic effect is unclear. PRINCIPAL FINDINGS: We generated astrocytoma subclones that express set levels of CB(1) and CB(2), and found that cannabinoid...

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Main Authors: Cudaback, Eiron, Marrs, William, Moeller, Thomas, Stella, Nephi
格式: Artigo
語言:Inglês
出版: Public Library of Science 2010
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806825/
https://ncbi.nlm.nih.gov/pubmed/20090845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008702
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