CD4+ levels control the odds of induction of humoral immune responses to tracer doses of therapeutic antibodies

Rapidly increasing number of therapeutic antibodies are being repurposed to imaging probes for noninvasive diagnosis, as well as monitoring during treatment or disease recurrence. Though antibody-based imaging involves tracer doses (~3 log lower than therapeutic doses), and immune responses are seve...

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Bibliographic Details
Published in:PLoS One
Main Authors: Srinivasula, Sharat, Gabriel, Erin, Kim, Insook, DeGrange, Paula, St Claire, Alexis, Mallow, Candace, Donahue, Robert E., Paik, Chang, Lane, H. C., Di Mascio, Michele
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679608/
https://ncbi.nlm.nih.gov/pubmed/29121114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187912
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