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CD4+ levels control the odds of induction of humoral immune responses to tracer doses of therapeutic antibodies

Rapidly increasing number of therapeutic antibodies are being repurposed to imaging probes for noninvasive diagnosis, as well as monitoring during treatment or disease recurrence. Though antibody-based imaging involves tracer doses (~3 log lower than therapeutic doses), and immune responses are seve...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Srinivasula, Sharat, Gabriel, Erin, Kim, Insook, DeGrange, Paula, St Claire, Alexis, Mallow, Candace, Donahue, Robert E., Paik, Chang, Lane, H. C., Di Mascio, Michele
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679608/
https://ncbi.nlm.nih.gov/pubmed/29121114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187912
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