Decreases in IL-7 levels during antiretroviral treatment of HIV infection suggest a primary mechanism of receptor-mediated clearance

IL-7 is essential for T-cell homeostasis. Elevated serum IL-7 levels in lymphopenic states, including HIV infection, are thought to be due to increased production by homeostatic feedback, decreased receptor-mediated clearance, or both. The goal of this study was to understand how immune reconstituti...

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Bibliografiske detaljer
Main Authors: Hodge, Jessica N., Srinivasula, Sharat, Hu, Zonghui, Read, Sarah W., Porter, Brian O., Kim, Insook, Mican, JoAnn M., Paik, Chang, DeGrange, Paula, Di Mascio, Michele, Sereti, Irini
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2011
Fag:
Immunobiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179394/
https://ncbi.nlm.nih.gov/pubmed/21778338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-12-323600
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