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Enantiomeric radiochemical synthesis of R and S (1-(6-amino-9H-purin-9-yl)-3-fluoropropan-2-yloxy)methylphosphonic acid (FPMPA)

Therapy for human immunodeficiency virus (HIV)-infected patients requires chronic multidrug administration. The eventual failure of therapy in some patients has brought into question the tissue concentration of the drugs. With an appropriately radiolabeled compound, we could utilize positron emissio...

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Détails bibliographiques
Auteurs principaux: Kiesewetter, Dale O., Knudson, Kathleen, Collins, Matt, Srinivasula, Sharat, Lim, Esther, Di Mascio, Michele
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735059/
https://ncbi.nlm.nih.gov/pubmed/19724660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jlcr.1505
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