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Enantiomeric radiochemical synthesis of R and S (1-(6-amino-9H-purin-9-yl)-3-fluoropropan-2-yloxy)methylphosphonic acid (FPMPA)

Therapy for human immunodeficiency virus (HIV)-infected patients requires chronic multidrug administration. The eventual failure of therapy in some patients has brought into question the tissue concentration of the drugs. With an appropriately radiolabeled compound, we could utilize positron emissio...

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Detalhes bibliográficos
Main Authors: Kiesewetter, Dale O., Knudson, Kathleen, Collins, Matt, Srinivasula, Sharat, Lim, Esther, Di Mascio, Michele
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735059/
https://ncbi.nlm.nih.gov/pubmed/19724660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jlcr.1505
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