In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming

Aging is the major risk factor for many human diseases. In vitro studies have demonstrated that cellular reprogramming to pluripotency reverses cellular age, but alteration of the aging process through reprogramming has not been directly demonstrated in vivo. Here, we report that partial reprogrammi...

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書誌詳細
出版年:Cell
主要な著者: Ocampo, Alejandro, Reddy, Pradeep, Martinez-Redondo, Paloma, Platero-Luengo, Aida, Hatanaka, Fumiyuki, Hishida, Tomoaki, Li, Mo, Lam, David, Kurita, Masakazu, Beyret, Ergin, Araoka, Toshikazu, Vazquez-Ferrer, Eric, Donoso, David, Roman, Jose Luis, Xu, Jinna, Esteban, Concepcion Rodriguez, Nuñez, Gabriel, Delicado, Estrella Nuñez, Campistol, Josep M., Guillen, Isabel, Guillen, Pedro, Belmonte, Juan Carlos Izpisua
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679279/
https://ncbi.nlm.nih.gov/pubmed/27984723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.11.052
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