Persistence of Pancreatic Insulin mRNA Expression and Proinsulin Protein in Type 1 Diabetes Pancreata

The canonical notion that type 1 diabetes (T1D) results following a complete destruction of β-cells has recently been questioned as small amounts of C-peptide are detectable in patients with longstanding disease. We analyzed protein and gene expression levels for proinsulin, insulin, C-peptide and i...

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Foilsithe in:Cell Metab
Main Authors: Wasserfall, Clive, Nick, Harry S., Campbell-Thompson, Martha, Beachy, Dawn, Haataja, Leena, Kusmartseva, Irina, Posgai, Amanda, Beery, Maria, Rhodes, Christopher, Bonifacio, Ezio, Arvan, Peter, Atkinson, Mark
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679224/
https://ncbi.nlm.nih.gov/pubmed/28877460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2017.08.013
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