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Persistence of Pancreatic Insulin mRNA Expression and Proinsulin Protein in Type 1 Diabetes Pancreata
The canonical notion that type 1 diabetes (T1D) results following a complete destruction of β-cells has recently been questioned as small amounts of C-peptide are detectable in patients with longstanding disease. We analyzed protein and gene expression levels for proinsulin, insulin, C-peptide and i...
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Publicado no: | Cell Metab |
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Main Authors: | , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5679224/ https://ncbi.nlm.nih.gov/pubmed/28877460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2017.08.013 |
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