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STING-associated vasculopathy develops independently of IRF3 in mice
Patients with stimulator of interferon genes (STING)–associated vasculopathy with onset in infancy (SAVI) develop systemic inflammation characterized by vasculopathy, interstitial lung disease, ulcerative skin lesions, and premature death. Autosomal dominant mutations in STING are thought to trigger...
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| 發表在: | J Exp Med |
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| Main Authors: | , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Rockefeller University Press
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5679177/ https://ncbi.nlm.nih.gov/pubmed/28951494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20171351 |
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