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The potential of targeting Sin3B and its associated complexes for cancer therapy
INTRODUCTION: Sin3B serves as a scaffold for chromatin-modifying complexes that repress gene transcription to regulate distinct biological processes. Sin3B-containing complexes are critical for cell cycle withdrawal, and abrogation of Sin3B-dependent cell cycle exit impacts tumor progression. AREAS...
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| Udgivet i: | Expert Opin Ther Targets |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5679076/ https://ncbi.nlm.nih.gov/pubmed/28956957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14728222.2017.1386655 |
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