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The potential of targeting Sin3B and its associated complexes for cancer therapy

INTRODUCTION: Sin3B serves as a scaffold for chromatin-modifying complexes that repress gene transcription to regulate distinct biological processes. Sin3B-containing complexes are critical for cell cycle withdrawal, and abrogation of Sin3B-dependent cell cycle exit impacts tumor progression. AREAS...

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Detalhes bibliográficos
Publicado no:Expert Opin Ther Targets
Main Authors: Cantor, David J, David, Gregory
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679076/
https://ncbi.nlm.nih.gov/pubmed/28956957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14728222.2017.1386655
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